Although I think comparisons between non-interactive media forms and interactive entertainment tend to be lame, I think the short and simple Flash-based games that have become common over the last couple of years do bear some resemblance with jokes or single-panel cartoons.

Usually, these games are crude (although they are often quite effective at conveying a message, more so than most games: who can forget the hilarious Gulf War 2?)

But sometimes, they can be like poems: like the lovely Fly Guy with it's wonderfully simple interactions with various people and objects, or like the amazing Orisinal, which features many small, but delightful mini-games.

If that isn't your cup of tea, kick ass as the famous Xiao Xiao Stick Figure.

(Partially from Web Zen, via the excellent BoingBoing.)