Will Wright held a talk at TED 2007 called 'Toys that make worlds'. The video of that talk has just been posted on TED.com. I haven't seen it yet myself, but if it's like some of the talks Will has held at GDC over the years, it should be excellent. From the description:

In a friendly, high-speed presentation, Will Wright demos his newest game, Spore, which promises to dazzle users even more than his previous masterpieces. Here Wright encourages users to create not households, as in The Sims, or cities, as in SimCity, but the entire universe, from single-celled life forms to galactic physics. While guiding us through his mesmerizing beta, Wright shares his thoughts on Montessori schools, Darwinian theory and long-term thinking, emphasizing, throughout, that Spore is not so much a game as an opportunity for discovery -- "an imagination amplifier."